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Image Search Results
Journal: Scientific Reports
Article Title: Effects of Black Raspberries and Their Ellagic Acid and Anthocyanin Constituents on Taxane Chemotherapy of Castration-Resistant Prostate Cancer Cells
doi: 10.1038/s41598-019-39589-1
Figure Lengend Snippet: Effects of black raspberry extract (BRB), protocatechuic acid (PCA), ellagic acid (EA), and cabazitaxel (CBZ) on microtubule assembly in vitro . Tubulin polymerization was measured by fluorescence intensity at 60 minutes of exposure to 10–1,000 μg/mL black raspberry extract ( A ), 10 μg/mL protocatechuic acid ( C ), and 10 μM ellagic acid and 100 nM cabazitaxel ( E ), or combinations of 100 nM cabazitaxel with 1 mg/mL black raspberry extract ( B ), 10 μg/mL protocatechuic acid ( D ), and 10 μM ellagic acid ( F ). Data are mean values ± SD of 3–7 repeat measurements at 1 minute intervals.
Article Snippet: Effects of compounds on
Techniques: In Vitro, Fluorescence
Journal: Scientific Reports
Article Title: Effects of Black Raspberries and Their Ellagic Acid and Anthocyanin Constituents on Taxane Chemotherapy of Castration-Resistant Prostate Cancer Cells
doi: 10.1038/s41598-019-39589-1
Figure Lengend Snippet: Combination effects of black raspberry extract ( A ) or ellagic acid ( B ) and CBZ on tubulin polymerization in 22Rv1 cells. Microtubules (green) were visualized by confocal microscopy with images enhanced for brightness and contrast. Binding affinity of docetaxel ( C ) and ellagic acid ( D ) for tubulin. This was determined by surface plasmon resonance and response-concentration plots are shown.
Article Snippet: Effects of compounds on
Techniques: Confocal Microscopy, Binding Assay, SPR Assay, Concentration Assay